Androgena alopecija – nasledni gubitak kose

Androgenetic alopecia, also known as hereditary baldness or androgenic hair loss, is the most common form of hair thinning in both men and women.

The pattern of hair loss differs between men and women. In men, it typically begins with a receding hairline in the frontal area (commonly referred to as “temples”) and thinning at the crown. As the condition progresses, these two areas may merge, forming a characteristic pattern of baldness.

In women, on the other hand, hair loss is usually more uniform and diffuse, most commonly affecting the top of the scalp without distinct bald patches.

The causes of androgenetic alopecia are complex and not yet fully understood, although hormones are known to play a key role.

The primary “culprit” is dihydrotestosterone (DHT) – a hormone formed by the conversion of testosterone through the enzyme 5-alpha-reductase. DHT gradually shortens the growth phase of hair follicles, leading to hair thinning and eventually permanent hair loss.

In women, the enzyme aromatase also plays a role by converting androgens into estrogens. Although estrogens have different effects than DHT, in certain cases they may contribute to hair growth changes similar to those caused by androgens.